1 In addition to the criteria listed above, it is helpful for quantitation purposes if the compound selected as the standard also has the properties of a primary analytical standard, for example potassium hydrogen phthalate (KHP), which is available in pure form, is a crystalline solid at room temperature and can be dried to remove waters of hydration. While it has improved performance as a quantitation standard compared with TMS or dioxane, it has been shown to absorb to glass so stock solutions may have stability problems. Mnova 14 is a major release implementing new features in most plugins and fixed several bugs.
HIDE REFERENCE PEAK INMR SOFTWARE
Mnova is a multivendor software suite designed for combined NMR, LC/GC/MS and Electronic & Vibrational Spectroscopic techniques.
TMSP is a water soluble chemical shift reference. A top class software suite to process your analytical chemistry data. Therefore it is difficult to prepare a standard solution for which the concentration is known with high accuracy. However they do not make good quantitation standards because they suffer from high volatility. TMS and dioxane are chemical shift reference compounds commonly used in organic solvents. The structures of several common NMR chemical shift and quantitation standards are shown in the figure below.
The requirement for lack of overlap means that most standards have simple NMR spectra, often producing only singlet resonances. The analyte concentration can then be determined relative to this standard compound. With NMR, we need only to have available any pure standard compound (which can be structurally unrelated to our analyte) that contains the nucleus of interest and has a resonance that does not overlap those of our analyte.
0 kommentar(er)
